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societal impact

Our field work in Africa will provide valuable information on the spread of Plasmodium isolates that are resistant to artemisinin derivatives as well as to other drugs effective for treating malaria. These data should allow us to swiftly develop new control strategies in order to limit the burden of these resistant clones. A better understanding of the biology of resistant parasites is also essential to devise new pharmacological strategies.

Our more fundamental work on immunity to Toxoplasma gondii and Plasmodium has the potential to uncover novel pathways / molecules by which intracellular parasites manipulate presentation of their own antigens, modulate immune responses and, more generally, subvert their host. These molecules could represent new targets for therapeutic approaches and our data could inform more rational vaccine design.

Last updated June 28, 2017

Centre de physiopathologie de Toulouse Purpan - CHU Purpan - BP 3028 31024 Toulouse Cedex 3
Inserm University of Toulouse Université Toulouse III - Paul Sabatier