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16 déc.

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Inflammatory diseases of the central nervous system: mechanisms and therapy

Heads : R. Liblau & A. Saoudi


 








Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that usually begins in young adulthood and progressively leads to disability in most patients. Due to its increasing prevalence, its chronic course, and the partial effect of current disease-modifying drugs, MS has major socio-economical consequences. The overarching objective of our team is to resolve the pathophysiology of inflammatory diseases that target the CNS, with a particular focus on MS as well as other CNS autoimmune or infectious diseases.


 

T cells in autoimmune diseases of the CNS: migration, functions and regulation


further reading…

 

 

Role of TCR signaling molecules in inflammatory diseases of the CNS

further reading…

 

 

Functional genomics and biomarkers of MS treatment

further reading…

 

 

Transcription factors in normal and pathological immune responses

further reading…

 


Last updated November 9, 2016


Centre de physiopathologie de Toulouse Purpan - CHU Purpan - BP 3028 31024 Toulouse Cedex 3
Inserm University of Toulouse Université Toulouse III - Paul Sabatier