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CPTP Présentation


Directeur : Roland LIBLAU.
Directeurs Adjoints : Paola ROMAGNOLI & Jacques IZOPET

Le Centre de Physiopathologie de Toulouse-Purpan (CPTP) a été l'un des premiers Centres de Recherche biomédicale créés par l'Inserm en 2002... la suite...

Dernières publications

Aloulou M, Carr EJ, Gador M, Bignon A, Liblau RS, Fazilleau N and Linterman MA.
Follicular regulatory T-cells can be specific for the immunizing antigen and derive from naive T-cells.
Nat Commun.2016 Jan 28;7:10579. doi: 10.1038/ncomms10579.

Martin-Blondel G, Brassat D, Bauer J, Lassmann H, Liblau RS.
CCR5 blockade for neuro-inflammatory diseases: above and beyond HIV control.
Nat Rev Neurol.2016 In press.

Mansuy JM, Gallian P, Dimeglio C, Sauné K, Arnaud C, Pelletier B, Morel P, Legrand D, Tiberghien P , Izopet J.
A nationwide survey of hepatitis E virus infection in French blood donors.
Hepatology.2016 In press.

Joncker NT, Bettini S, Boulet D, Guiraud M, Guerder S.
The site of tumor development determines immunogenicity via temporal mobilization of antigen laden dendritic cells in draining lymph nodes.
Eur J Immunol. 2015 Dec 2. doi: 10.1002/eji.201545797.

Ferré CA, Davezac N, Thouard A, Peyrin JM, Belenguer P, Miquel MC, Gonzalez-Dunia D, Szelechowski M.
Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential.
FASEB J. 2015 Dec 23. pii: fj.15-279620.

Decque A, Joffre O, Magalhaes JG, Cossec JC, Blecher-Gonen R, Lapaquette P, Silvin A, Manel N, Joubert PE, Seeler JS, Albert ML, Amit I, Amigorena S, Dejean A.
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing.
Nat Immunol. 2015 Dec 14. doi: 10.1038/ni.3342.

Siewiera J, Gouilly J, Hocine HR, Cartron G, Levy C, Al-Daccak R, Jabrane-Ferrat N.
Natural cytotoxicity receptor splice variants orchestrate the distinct functions of human natural killer cell subtypes.
Nat Commun. 2015 Dec 15;6:10183. doi: 10.1038/ncomms10183.

Lopez J, Bittame A, Massera C, Vasseur V, Effantin G, Valat A, Buaillon C, Allart S, Fox BA, Rommereim LM, Bzik DJ, Schoehn G, Weissenhorn W, Dubremetz JF, Gagnon J, Mercier C, Cesbron-Delauw MF, Blanchard N
Intravacuolar membranes regulate CD8 T cell recognition of membrane-bound Toxoplasma gondii protective antigen.
Cell Rep 2015 Nov 23. pii: S2211-1247(15)01288-7. doi: 10.1016/j.celrep.2015.11.001.

Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S.
The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens.
J Immunol. 2015 Sep 1;195(5):1964-73. doi: 10.4049/jimmunol.1401683. Epub 2015 Jul 24.

Caminade AM, Fruchon S, Turrin CO, Poupot M, Ouali A, Maraval A, Garzoni M, Maly M, Furer V, Kovalenko V, Majoral JP, Pavan GM, Poupot R.
The key role of the scaffold on the efficiency of dendrimer nanodrugs.
Nat Commun. 2015 Jul 14;6

Vasconcelos Z, Müller S, Guipouy D, Yu W, Christophe C, Gadat S, Valitutti S, Dupré L.
Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing.
Cell Rep. 2015 Jun 9;11(9):1474-85. doi: 10.1016/j.celrep.2015.05.002. Epub 2015 May 28.

Thiault N, Darrigues J, Adoue V, Gros M, Binet B, Perals C, Leobon B, Fazilleau N, Joffre OP, Robey EA, van Meerwijk JP, Romagnoli P.
Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors.
Nat Immunol. 2015 May 4. doi: 10.1038/ni.3150.

Liblau RS, Vassalli A, Seifinejad A, Tafti M
Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy
Lancet Neurol. 2015 Mar;14(3):318-28. doi: 10.1016/S1474-4422(14)70218-2.

Waisman A, Liblau RS, Becher B
Innate and adaptive immune responses in the CNS
Lancet Neurol 2015; 14: 945–55

Malet-Engra G, Yu W, Oldani A, Rey-Barroso J, Gov NS, Scita G, Dupré L.
Collective cell motility promotes chemotactic prowess and resistance to chemorepulsion.
Curr Biol. 2015 Jan 19;25(2):242-50. doi: 10.1016/j.cub.2014.11.030.

Iriart X, Challan Belval T, Fillaux J, Esposito L, Lavergne RA, Cardeau-Desangles I, Roques O, Del Bello A, Cointault O, Lavayssière L, Chauvin P, Menard S, Magnaval JF, Cassaing S, Rostaing L, Kamar N, Berry A.
Risk factors of Pneumocystis pneumonia in solid organ recipients in the era of the common use of posttransplantation prophylaxis.
Am J Transplant. 2015 Jan;15(1):190-9. doi: 10.1111/ajt.12947.

Joulia R, Gaudenzio N, Rodrigues M, Lopez J, Blanchard N, Valitutti S, Espinosa E.
Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence.
Nat Commun.
2015 Jan 28;6:6174. doi: 10.1038/ncomms7174.

Abravanel F, Lhomme S, Rostaing L, Kamar N, Izopet J.
Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse.
Clin Infect Dis.
2015 Jan 1;60(1):96-9. doi: 10.1093/cid/ciu742.

Szelechowski M, Bétourné A, Monnet Y, Ferré CA, Thouard A, Foret C, Peyrin JM, Hunot S, Gonzalez-Dunia D.
A viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease.
Nat Commun. 2014 Oct 21;5:5181. doi: 10.1038/ncomms6181.

Kamar N, Izopet J.
Does chronic hepatitis E virus infection exist in immunocompetent patients?
Hepatology. 2014 Jul;60(1):427. doi: 10.1002/hep.26927. Epub 2014 May 27.

Chakarov S, Fazilleau N.
Monocyte-derived dendritic cells promote T follicular helper cell differentiation.
EMBO Mol Med. 2014 May 1;6(5):590-603. doi: 10.1002/emmm.201403841.

Kamar N, Izopet J, Tripon S, Bismuth M, Hillaire S, Dumortier J, Radenne S, Coilly A, Garrigue V, D'Alteroche L, Buchler M, Couzi L, Lebray P, Dharancy S, Minello A, Hourmant M, Roque-Afonso AM, Abravanel F, Pol S, Rostaing L, Mallet V.
Ribavirin for chronic hepatitis E virus infection in transplant recipients.
N Engl J Med. 2014 Mar 20;370(12):1111-20. doi: 10.1056/NEJMoa1215246.

Laffont S, Rouquié N, Azar P, Seillet C, Plumas J, Aspord C, Guéry JC.
X-Chromosome complement and estrogen receptor signaling independently contribute to the enhanced TLR7-mediated IFN-α production of plasmacytoid dendritic cells from women.
J Immunol. 2014 Dec 1;193(11):5444-52. doi: 10.4049/jimmunol.1303400. Epub 2014 Oct 22.

Robert V, Triffaux E, Paulet PE, Guéry JC, Pelletier L, Savignac M.
Protein kinase C-dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions.
J Allergy Clin Immunol. 2014 Apr;133(4):1175-83. doi: 10.1016/j.jaci.2013.10.038. Epub 2013 Dec 22.


Kamar N, Dalton HR, Abravanel F, Izopet J.
Hepatitis E virus infection.
Clin Microbiol Rev. 2014 Jan;27(1):116-38. doi: 10.1128/CMR.00057-13.







 





Evénements

Séminaires Séminaire le 04/10/2016 à 11h00

présentée par : Brigitte Autran

à la recherche des réservoirs de VIH

Salle P. Druet, CPTP Bât A rdc, CHU Purpan

Localisation du CPTP

CPTP
INSERM UMR 1043 / CNRS UMR 5282
Université Toulouse III
CHU Purpan
BP 3028
31024 Toulouse CEDEX 03
Tél. : 05 62 74 45 45
Fax : 05 62 74 45 58

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Date de mise à jour 25 février 2016


Centre de physiopathologie de Toulouse Purpan - CHU Purpan - BP 3028 31024 Toulouse Cedex 3
Inserm Université de Toulouse Université Toulouse III - Paul Sabatier