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16 sept.

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CPTP Présentation

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Directeur : Roland LIBLAU.
Directrices-Adjointes :
Marie-Paule ROTH et Nathalie VERGNOLLE.

 Le Centre de Physiopathologie de Toulouse-Purpan (CPTP) a été l'un des premiers Centres de Recherche biomédicale créés par l'Inserm en 2002. la suite...

Dernières publications

Viguier M, Bachelez H, Poirier B, Kagan J, Battistella M, Aubin F, Touzé A, Carmagnat M, Francès C, Gougeon ML, Fazilleau N.
Peripheral and Local Human Papillomavirus 16-Specific CD8+ T-Cell Expansions Characterize Erosive Oral Lichen Planus.
J Invest Dermatol. 2014 Sep 10. doi: 10.1038/jid.2014.397

Huang J, Brameshuber M, Zeng X, Xie J, Li QJ, Chien YH, Valitutti S, Davis MM.
A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells.
Immunity. 2013 Nov 14;39(5):846-57. doi: 10.1016/j.immuni.2013.08.036.

Kamar N1, Izopet J, Tripon S, Bismuth M, Hillaire S, Dumortier J, Radenne S, Coilly A, Garrigue V, D'Alteroche L, Buchler M, Couzi L, Lebray P, Dharancy S, Minello A, Hourmant M, Roque-Afonso AM, Abravanel F, Pol S, Rostaing L, Mallet V.
Ribavirin for chronic hepatitis E virus infection in transplant recipients.
N Engl J Med. 2014 Mar 20;370(12):1111-20. doi: 10.1056/NEJMoa1215246.

Chakarov S, Fazilleau N.
Monocyte-derived dendritic cells promote T follicular helper cell differentiation.
EMBO Mol Med., 2014 Apr 11

Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, Kim S, Duru V, Bouchier C, Ma L, Lim P, Leang R, Duong S, Sreng S, Suon S, Chuor CM, Bout DM, Ménard S, Rogers WO, Genton B, Fandeur T, Miotto O, Ringwald P, Le Bras J, Berry A, Barale JC, Fairhurst RM, Benoit-Vical F, Mercereau-Puijalon O, Ménard D.
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
Nature. 2014 Jan 2;505(7481):50-5. doi: 10.1038/nature12876.

Poli M, Asperti M, Naggi A, Campostrini N, Girelli D, Corbella M, Benzi M, Besson-Fournier C, Coppin H, Maccarinelli F, Finazzi D, Arosio P.
Glycol-split non-anticoagulat heparins are inhibitors of hepcidin expression in vitro and in vivo.
Blood. 2014 Jan 7. [Epub ahead of print]

Meynard D, Babitt JL, Lin HY.
The liver: conductor of systemic iron balance.
Blood. 2014 Jan 9;123(2):168-76. doi: 10.1182/blood-2013-06-427757. Epub 2013 Nov 7.

Bertrand F, Müller S, Roh KH, Laurent C, Dupré L, Valitutti S.
An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse.
Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6073-8. doi: 10.1073/pnas.1218640110. Epub 2013 Mar 27.

Prugnolle F, Rougeron V, Becquart P, Berry A, Makanga B, Rahola N, Arnathau C, Ngoubangoye B,Menard S, Willaume E, Ayala FJ, Fontenille D, Ollomo B, Durand P, Paupy C, Renaud F.
Diversity, host switching and evolution of Plasmodium vivax infecting African great apes.
Proc Natl Acad Sci U S A. 2013 May 14;110(20):8123-8. doi: 10.1073/pnas.1306004110. Epub 2013 May 1.

Gaudenzio N, Laurent C, Valitutti S, Espinosa E.
Human mast cells drive memory CD4+ T cells toward an inflammatory IL-22+ phenotype.
J Allergy Clin Immunol. 2013 May;131(5):1400-7.e11. doi: 10.1016/j.jaci.2013.01.029. Epub 2013 Mar 19.

Pasquet L, Douet JY, Sparwasser T, Romagnoli P, van Meerwijk JP.
Long-term prevention of chronic allograft rejection by regulatory T-cell immunotherapy involves host Foxp3-expressing T cells.
Blood. 2013 May 23;121(21):4303-10. doi: 10.1182/blood-2012-08-452037. Epub 2013 Apr 11.

Liblau RS, Gonzalez-Dunia D, Wiendl H, Zipp F.
Neurons as targets for T cells in the nervous system.
Trends Neurosci. 2013 Jun;36(6):315-24. doi: 10.1016/j.tins.2013.01.008. Epub 2013 Mar 13. Review.

Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.
Hepatology. 2013 Aug 1. doi: 10.1002/hep.26648. [Epub ahead of print]

Garcia S, Dirat B, Tognacci T, Rochet N, Mouska X, Bonnafous S, Patouraux S, Tran A, Gual P, Le Marchand-Brustel Y, Gennero I, Gouze E.
Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Sci Transl Med. 2013 Sep 18;5(203):203ra124. doi: 10.1126/scitranslmed.3006247.

Latour C, Besson-Fournier C, Rouquie N, Kautz L, Aguilar-Martinez P, Roth MP, Coppin H.
Inactivating Hfe Totally Abolishes Hepcidin Production and Further Aggravtes Iron Overload In Bmp6-Deficient Mice.
Blood. Nov 15, 2013 vol. 122 N. 21 178

Kamar N, Izopet J.
Does chronic hepatitis E virus infection exist in immunocompetent patients?
Hepatology. 2013 Nov 9. doi: 10.1002/hep.26927. [Epub ahead of print]

Robert V, Triffaux E, Paulet PE, Guéry JC, Pelletier L, Savignac M.
Protein kinase C-dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions.
J Allergy Clin Immunol. 2013 Dec 20. pii: S0091-6749(13)01699-0. doi: 10.1016/j.jaci.2013.10.038. [Epub ahead of print]

Martin P, Marcq I, Magistro G, Penary M, Garcie C, Payros D, Boury M, Olier M, Nougayrede JP, Audebert M, Chalut C, Schubert S and Oswald E.
Interplay between siderophores and colibactin genotoxin biosynthetic pathways in Escherichia coli.
PLoS Pathog, 2013;9(7):e1003437

Seillet C, Rouquié N, Foulon E, Douin-Echinard V, Krust A, Chambon P, Arnal JF, Guéry JC, Laffont S.
Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor .
J Immunol. 2013 Jun 1;190(11):5459-70.

Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Testosterone perturbs systemic iron balance through activation of EGFR signaling in the liver and repression of hepcidin.
Hepatology. 2013 Aug 1. doi: 10.1002/hep.26648.

Jérôme Boué, Lilian Basso, Nicolas Cenac, Catherine Blanpied, Malvyne Rolli-Derkinderen, Michel Neunlist, Nathalie Vergnolle, Gilles Dietrich.
Endogenous Regulation of Visceral Pain via Production of Opiods by Colitogenic CD4+ T Cells in Mice
.

Gastroenterology Available online 18 September 2013.

Lombardelli L, Aguerre-Girr M, Logiodice F, Kullolli O, Casart Y, Polgar B, Berrebi A, Romagnani S, Maggi E, Le Bouteiller P, Piccinni MP.
HLA-G5 Induces IL-4 Secretion Critical for Successful Pregnancy through Differential Expression of ILT2 Receptor on Decidual CD4+ T Cells and Macrophages.
J Immunol. 2013 Sep 6.

Feliu V, Vasseur V, Grover HS, Chu HH, Brown MJ, Wang J, Boyle JP, Robey EA, Shastri N, Blanchard N
Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite.
PLoS Pathogens 2013 9(6): e1003449.

Bertrand F, Müller S, Roh KH, Laurent C, Dupré L, Valitutti S.
An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse.
Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6073-8. Epub 2013 Mar 27.

Pasquet L, Douet JY, Sparwasser T, Romagnoli P, van Meerwijk JP.
Long term prevention of chronic allograft rejection by regulatory T cell immunotherapy involves host Foxp3-expressing T cells.
Blood. 2013 Apr 11. [Epub ahead of print]

Johan Siewiera, Hicham El Costa, Julie Tabiasco, Alain Berrebi, Géraldine Cartron, Philippe Le Bouteiller, Nabila Jabrane-Ferrat
Human Cytomegalovirus Infection Elicits New Decidual Natural Killer Cell Effector Functions
PLOS Pathogens 10.1371/journal.ppat.1003257

Liblau RS, Gonzalez-Dunia D, Wiendl H, Zipp F.
Neurons as targets for T cells in the nervous system.
Trends Neurosci. 2013 Mar 8. pii: S0166-2236(13) [Epub ahead of print]

Evénements

Séminaires Séminaire le 18/09/2014 à 11h00

présentée par : Siamon Gordon

Séminaire de Prestige: Macrophages in tissues: Heterogeneity and functions

S. Baudot


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CPTP
INSERM UMR 1043 / CNRS UMR 5282
Université Toulouse III
CHU Purpan
BP 3028
31024 Toulouse CEDEX 03
Tél. : 05 62 74 45 45
Fax : 05 62 74 45 58

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Date de mise à jour 16 septembre 2014


Centre de physiopathologie de Toulouse Purpan - CHU Purpan - BP 3028 31024 Toulouse Cedex 3
Inserm Université de Toulouse Université Toulouse III - Paul Sabatier